Concentration Details

Metabolite
HMDB0004400 (5-Acetylamino-6-amino-3-methyluracil)
Biospecimen
Urine
Status
Detected and Quantified
Data source
Referenced
Concentration
5.06 +/- 0.13 umol/mmol creatinine
Age
Adult (>18 years old)
Sex
Both
Condition
Normal
Comments
Healthy volunteers were given a 2.5 mg / kg dose of caffeine as a cup of coffee (Nescafe Gold) after a 1-day xanthine-free diet. Spot urine samples were collected 8 h after the caffeine intake.
References
    1. Nyeki A, Biollaz J, Kesselring UW, Decosterd LA: Extractionless method for the simultaneous high-performance liquid chromatographic determination of urinary caffeine metabolites for N-acetyltransferase 2, cytochrome P450 1A2 and xanthine oxidase activity assessment. J Chromatogr B Biomed Sci Appl. 2001 May 5;755(1-2):73-84. [PubMed:11393735 ]