Concentration Details

Metabolite
HMDB0000112 (gamma-Aminobutyric acid)
Biospecimen
Urine
Status
Detected and Quantified
Data source
Referenced
Concentration
0.25 +/- 0.20 umol/mmol creatinine
Age
Adult (>18 years old)
Sex
Not Specified
Condition
Normal
References
    1. Nicholson-Guthrie CS, Guthrie GD, Sutton GP, Baenziger JC: Urine GABA levels in ovarian cancer patients: elevated GABA in malignancy. Cancer Lett. 2001 Jan 10;162(1):27-30. [PubMed:11121859 ]
    2. Silwood CJ, Lynch E, Claxson AW, Grootveld MC: 1H and (13)C NMR spectroscopic analysis of human saliva. J Dent Res. 2002 Jun;81(6):422-7. [PubMed:12097436 ]
    3. Campollo O, MacGillivray BB, McIntyre N: [Association of plasma ammonia and GABA levels and the degree of hepatic encephalopathy]. Rev Invest Clin. 1992 Oct-Dec;44(4):483-90. [PubMed:1485027 ]
    4. Gibson KM: Gamma-hydroxybutyric aciduria: a biochemist's education from a heritable disorder of GABA metabolism. J Inherit Metab Dis. 2005;28(3):247-65. [PubMed:15868461 ]
    5. Wang Z, Silverman RB: Syntheses and evaluation of fluorinated conformationally restricted analogues of GABA as potential inhibitors of GABA aminotransferase. Bioorg Med Chem. 2006 Apr 1;14(7):2242-52. Epub 2005 Nov 28. [PubMed:16314106 ]
    6. Glodzik-Sobanska L, Slowik A, Kozub J, Sobiecka B, Urbanik A, Szczudlik A: GABA in ischemic stroke. Proton magnetic resonance study. Med Sci Monit. 2004 Jun;10 Suppl 3:88-93. [PubMed:16538207 ]
    7. Nisijima K, Ishiguro T: Cerebrospinal fluid levels of monoamine metabolites and gamma-aminobutyric acid in neuroleptic malignant syndrome. J Psychiatr Res. 1995 May-Jun;29(3):233-44. [PubMed:7473299 ]
    8. Sweatman BC, Farrant RD, Holmes E, Ghauri FY, Nicholson JK, Lindon JC: 600 MHz 1H-NMR spectroscopy of human cerebrospinal fluid: effects of sample manipulation and assignment of resonances. J Pharm Biomed Anal. 1993 Aug;11(8):651-64. [PubMed:8257730 ]
    9. Naini AB, Vontzalidou E, Cote LJ: Isocratic HPLC assay with electrochemical detection of free gamma-aminobutyric acid in cerebrospinal fluid. Clin Chem. 1993 Feb;39(2):247-50. [PubMed:8432013 ]
    10. Qureshi GA, Baig SM, Bednar I, Halawa A, Parvez SH: The neurochemical markers in cerebrospinal fluid to differentiate between aseptic and tuberculous meningitis. Neurochem Int. 1998 Feb;32(2):197-203. [PubMed:9542731 ]